Inability of Haemophilus haemolyticus to invade respiratory epithelial cells in vitro
نویسندگان
چکیده
منابع مشابه
Haemophilus haemolyticus Interaction with Host Cells Is Different to Nontypeable Haemophilus influenzae and Prevents NTHi Association with Epithelial Cells
Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen that resides in the upper respiratory tract and contributes to a significant burden of respiratory related diseases in children and adults. Haemophilus haemolyticus is a respiratory tract commensal that can be misidentified as NTHi due to high levels of genetic relatedness. There are reports of invasive disease from H. haemo...
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Haemophilus haemolyticus is generally considered a human commensal and is found in the nasopharynx of a minority of individuals as well as in subgingival plaque (7). Most authors consider H. haemolyticus to be either nonpathogenic (2, 4, 7, 18) or a rare pathogen (1). The latter assessment appears to be based on two reports of endocarditis from the early part of the 20th century (3, 13); howeve...
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Campylobacter jejuni is a common cause of serious diarrhoeal disease in humans, in contrast to the avian population, where exposure results in prolonged colonization at high density without disease. Colonized poultry present a significant source of infection to humans worldwide. The aim of this work was to compare the interaction of Campylobacter with primary intestinal cells from humans and po...
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Epithelial cells interact directly with bacteria in the environment and play a critical role in airway defense against microbial pathogens. In this study, we examined the response of respiratory epithelial cells to infection with nontypable Haemophilus influenzae. Using an in vitro cell culture model, we found that epithelial cell monolayers released significant quantities of IL-8 and expressed...
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We report seven cases of Haemophilus haemolyticus invasive disease detected in the United States, which were previously misidentified as nontypeable Haemophilus influenzae. All cases had different symptoms and presentations. Our study suggests that a testing scheme that includes reliable PCR assays and standard microbiological methods should be used in order to improve H. haemolyticus identific...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2016
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.000349